Our research
Our research focuses on understanding how cancer evolves, progresses, and becomes resistant to treatment. We study the genetic and non-genetic changes that shape these processes, using advanced computational and experimental approaches in genomics and epigenomics.
By uncovering the mechanisms that drive tumor diversity and evolution, our work aims to reveal fundamental principles of cancer biology and inform the development of more effective treatments.
Our laboratory's current projects include:
Investigating how non-genetic/epigenetic alterations, such as DNA methylation or chromatin regulation, affect pre-malignant and malignant cell states.
Examining the phenotypic plasticity of pre-malignant and malignant cells and how this plasticity contributes to cancer progression and therapy resistance.
Assessing how extrinsic factors, including the tumor microenvironment, shape pre-malignant and malignant cell states during cancer evolution.
Join our team.
Our goal is to build a diverse, collaborative community of scientists of all levels.